2 edition of Basophilic leukocytes in delayed hypersensitivity. found in the catalog.
Basophilic leukocytes in delayed hypersensitivity.
|LC Classifications||QP95 .W6|
|The Physical Object|
|Pagination||123 p., 6 plates.|
|Number of Pages||123|
|LC Control Number||67088403|
The term cutaneous basophil hypersensitivity (CBH) initially referred to a systemic but evanescent pattern of delayed-onset reactivity in guinea pigs . Dvorak HF, Mihm MC Jr: Basophilic leukocytes in allergic contact dermatitis. J Exp Med , Gershon RK, Askenase PW, Gershon MD: Requirement for vaso active amines for production of delayed-type hypersensitivity skin reactions. J Exp Med , The Third Regional Conference of Dermatology.
Delayed onset erythematous skin reactions elicited in guinea pigs early in the course of sensitization with azobenzenearsonate-protein conjugates or with protein antigens in incomplete Freund's adjuvant or in saline were found to have a characteristic morphology which sets them apart from delayed hypersensitivity and the classic antibody mediated reactions. Cited by: Books; JCB Journal of Cell Biology; in incomplete Freund's adjuvant or in saline were found to have a characteristic morphology which sets them apart from delayed hypersensitivity and the classic antibody mediated reactions. The principle feature was massive dermal infiltration with basophilic leukocytes. The principle feature was Cited by:
Related to delayed hypersensitivity response; Triggered by IgE binding to antigen; basophilic leukocyte, Basophil leukocyte, basophils, basophil, Basophil, Basophil, segmented (cell) Spanish: basófilo, segmentado, basófilo this collection now contains interlinked topic pages divided into a tree of 31 specialty books and a type of blood cell that lacks hemoglobin and is therefore colorless. Leukocytes are larger in size and fewer in number than erythrocytes; normally the blood has about of them per mm 3. In contrast to erythrocytes, leukocytes can move about .
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Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 29) Abstract Many forms of delayed-onset, lymphocyte-mediated hypersensitivity reactions in animals and man are characterized by an extensive infiltration of basophilic leukocytes [1–6].Cited by: 7. Basophilic leukocytes in delayed hypersensitivity.
Experimental studies in man using the skin window technique. Basophilic leukocytes constitute a significant proportion of the cellular infiltrates in many forms of delayed-in-onset hypersensitivity reactions in human beings, guinea pigs, and other animals.
In this paper, I review current information on the role of basophils in the reactions, and present similarities and differences between Jones-Mote and Cited by: Basophils comprised about one-third of the leukocytes infiltrating the 24 to h trichophytin skin test reactions of guinea pigs sensitized by a cutaneous T.
mentagrophytes infection. These results were comparable to the percentage of basophils counted in skin test lesions elicited by the contact agent dinitrochlorobenzene and are consistent with previously published descriptions of cutaneous basophil by: Basophilic leukocytes in delayed hypersensitivity reactions.
Participation of the basophil in hypersensitivity to antigen-antibody complexes, delayed hypersensitivity and contact allergy.
Passive transfer. Dvorak HF, Simpson BA, Bast RC, Leskowitz by: In contrast, guinea pigs immunized with mycobacterial adjuvants have classical tuberculin-type delayed hypersensitivity reactions, which contain few basophils.
This has led to a new classification of delayed responses, based largely on the presence or absence of by: Recently, however, we have found that several forms of delayed-onset cellmediated hypersensitivity in animals are characterized by an extensive infiltration of basophilic leukocytes (2).
Such reactions have been designated cutaneous basophil hypersensitivity or CBH 1 to distinguish them from true delayed hypersensitivity (DH) in which basophils. Very probably, basophilic leukocytes take part in autoimmune processes on the whole. The reason why basophilic cells have not previously been described in delayed hypersensitivity may be that the immune process has not been investigated by the skin window technique.
In biopsies the exudate may have been by: 3. III. Participation of the basophil in hypersensitivity to antigen-antibody complexes, delayed hypersensitivity, and contact by: Degranulation of basophilic leukocytes in allergic contact dermatitis reactions in.
By F. Dvorak, Martin and C. Mihm. Abstract. Delayed hypersensitivity has generally been regarded as a homogeneous group of reactions including reactivity to proteins such as tuberculin, contact allergy, resistance to infection with viruses and other Author: F.
Dvorak, Martin and C. Mihm. A variety of cell-mediated hypersensitivity reactions in experimental animals include a prominent infiltrate of basophilic leukocytes. This form of reactivity has been designated cutaneous basophil hypersensitivity and is favored when sensitization to several types of antigen is accomplished without the use of complete Freund's by: Value of the Cutaneous Basophil Hypersensitivity (CBH) Response for Distinguishing Weak basophilic leukocytes.
In this study we determined whether reactions as well as other forms of delayed-type hypersensitivity reactions [ 1,3 - All of the work on the CBH response in. In birds basophils appear to play an important role in early inflammatory and immediate hypersensitivity reactions, but differ from those in mammals by not contributing to delayed hypersensitivity.
They are crucial participants in cutaneous basophilic hyper-sensitivity reactions and in passive cutaneous and systemic by: A variety of cell-mediated hypersensitivity reactions in experimental animals include a prominent infiltrate of basophilic leukocytes.
This form of reactivity has been designated cutaneous basophil hypersensitivity and is favored when sensitization to several types of antigen is accomplished without the use of complete Freund's by: Passive transfer J Immunol () Wolf-JÃ¼rgensen, P.
Wolf-JÃ¼rgensen, Basophilic Leukocytes in Delayed Hypersensitivity Experimental Studies in Man Using the Skin Wound Technique () Munksgaard Copenhagen Colvin et al., R.B. Colvin, R.A. Johnson, M.C. Mihm, Jr H.F.
Dvorak, Role of the clotting system in cell Cited by: The results of studies conducted indicated that changes in the quantity and degranulation of basophilic leucocytes may be used along with skin allergic response of delayed hypersensitivity as one.
The appearance of basophils and eosinophils at the sites of late or delayed skin reaction was examined in 34 bronchial asthmatics.
Using guinea pigs, Author: Harold F Dvorak. A cutaneous basophil hypersensitivity response has been observed in rabbits immunized with bovine serum albumin and challenged intradermally with this antigen 7 days later.
The cellular response appears to be similar to cutaneous basophil hypersensitivity reported in Cited by: 9. The avian basophilic leukocyte: a review M.H. MAXWELL and G.W.
ROBERTSON Roslin Institute (Edinburgh), Roslin, Midlothian EH25 9PS, UK This paper reviews the current state of knowledge of the avian basophilic leukocyte.
It includes a description of the general morphology of the cell derived from light and electron microscopy. Abstract. The term cutaneous basophil hypersensitivity (CBH) initially referred to a systemic but evanescent pattern of delayed-onset reactivity in guinea pigs sensitized to protein antigens administered without mycobacterial adjuvants (Richerson et al.,; H.
Dvorak et al., ).When animals immunized in this fashion were skin tested 5–7 days later, sites of Cited by: 9. Abstract. A well-established expression of cell-mediated immunity has been separated from classical tuberculin type delayed hypersensitivity.
Originally called "Jones Mote " sensitivity (1), it has been renamed cutaneous basophil hypersensitivity (CBH) (2) to emphasize the large numbers of basophilic leukocytes that infiltrate the dermis in the skin lesions.Cutaneous basophil hypersensitivity Harold F. Dvorak, M.D.
Boston, Mass. Cutaneous 'basophil hypersensitivity (CBH) is a distinct form of lymphocyte- mediated hypersensitivity in guinea pigs, separate 'both from classic delayed hyper- sensitivity (DE) and from the well-known, antibody-mediated by: On the one hand, there are hypersensitivity diseases, which are characterized by excessive and undesirable reactions, produced by the immune system [ 4 ].
On the other hand, autoimmune diseases refer to the failure of the immunological tolerance mechanisms, causing reactions against own cells and tissues [ 5 ].Cited by: 2.